Royalty Portfolio

XOMA Royalty has an expansive portfolio of assets that provides us the right to future potential royalty and milestone payments.  These drug candidate assets are being developed by others.

While some information on these therapeutic candidates is restricted by confidentiality agreements, in the table below you will find links that offer more information about disclosed assets.  We provide this information for informational purposes only.

Commercial Assets

Marketer Asset Name Target Royalty Rate Clinical Trials Product Website  
Daré Bioscience DARE TO PLAY™ PDE-5 inhibitor Low single digit product website
Day One OJEMDA™ (tovorafenib) Pan-RAF inhibitor Mid-single digit clinical trials
Medexus IXINITY® Recombinant Factor IX Mid-single digit product website
Organon XACIATO™ Bacterial vaginal infection High single digit product website
Roche VABYSMO® (faricimab-svoa) Angiopoietin-2 and VEGF-A bispecific antibody 0.5% clinical trials
Talphera DSUVIA® (sufentanil sublingual tablet) Acute pain treatment 37.5-75% (DoD) clinical trials product website
Zevra MIPLYFFA™ (arimoclomol) Heat-shock protein amplifier Mid-single digit clinical trials product website

Late-Stage Assets

Developer Asset Name Target Royalty Rate Clinical Trials    
AstraZeneca Rilvegostomig (AZD2936) TIGIT/PD-1 bispecific antibody Undisclosed clinical trials
AVEO, an LG Chem company Ficlatuzumab (AV-299) HGF antibody Low single digit clinical trials
Castle Creek Biosciences D-Fi (FCX-007) Gene therapy <1.0% clinical trials
Chiesi & Gossamer Seralutinib Inhaled PDGFR, CSF1R, c-KIT inhibitor Low to mid-single digit, net clinical trials
Daré Bioscience Ovaprene® Hormone-free contraceptive Low single digit clinical trials
Johnson & Johnson Cetrelimab (JNJ-63723283) PD-1 antibody 0.75% clinical trials
Mirum Pharmaceuticals Volixibat Ileal bile acid transporter (IBAT) inhibitor Low to mid-single digit clinical trials
Oak Hill Bio OHB-607 Recombinant human IGF-I/IGFBP-3 Low to mid-single digit clinical trials
Recursion Pharmaceuticals REC-4881 Allosteric MEK1/2 inhibitor Low to mid-single digit clinical trials
Rezolute Ersodetug (RZ358) INSR antibody High single digit to mid teens clinical trials
Takeda Mezagitamab (TAK-079) CD-38 antibody Low single digit clinical trials
Takeda in Japan & Partner outside of Japan Osavampator Alpha-amino-3-hydroxy-5-methyl-4 isoxazole propionic acid (AMPA) positive allosteric modulator Low to mid-single digit clinical trials

Other Assets

Developer Asset Name Target Royalty Rate Clinical Trials    
Aronora AB023 Factor XI/Xia Low single digit clinical trials
Celyn Therapeutics KIN-8741 c-MET Not disclosed
Compugen COM902 TIGIT antibody Undisclosed clinical trials
Daré Bioscience Sildenafil cream, 3.6% PDE-5 inhibitor Low single digit clinical trials
Johnson & Johnson JNJ-89853413 Bispecific Vδ2 T-cell engager Low single digit clinical trials
Khora KIN-3248 FGFR None clinical trials
Khora Undisclosed CDK2/4 None
Khora Undisclosed CDK4 None
Lifordi LFD-200 VISTA ADC 0.75% clinical trials
Merck MK-4830 ILT-4 Not disclosed clinical trials
Moderna Undisclosed T-Cell Mid-single digit
Molecular Templates MT-0169 Anti-CD-38 immunotoxin 4% clinical trials
Monopar Therapeutics MNPR-101 Urokinase plasminogen activator receptor (uPAR) radioimmunotherapeutic None
Mosaica Therapeutics KIN-7136 MEK Not disclosed
National Resilience G03-52-01 Botulinum neurotoxin antibodies 15%
Oak Hill Bio Five early-stage assets Multiple targets Low to mid-single digit
Palobiofarma PBF-680 Adenosine A1 receptor inhibitor Low single digit clinical trials
Palobiofarma PBF-677 Adenosine A3 receptor inhibitor Low single digit clinical trials
Palobiofarma PBF-999 Adenosine A2a receptor/ PDE-10 inhibitor Low single digit clinical trials
Palobiofarma PBF-1129 Adenosine A2b receptor inhibitor Low single digit clinical trials
Palobiofarma PBF-1650 Adenosine A3 receptor inhibitor Low single digit clinical trials
Pfizer PF-08046052 Anti-EGFR bispecific γδ T-cell engager Low single digit clinical trials
Regeneron Vidutolimod (CMP-001) Virus-like particle containing a TLR9 agonist High single digit to double digit clinical trials
Rezolute AB101 Injectable basal insulin Low single digit
Rezolute RZ-402 Plasma kallikrein inhibitor Low single digit clinical trials
Twist Bioscience's 30+ partners 60+ early-stage assets Multiple targets 50% of up to low single digits